P3.03-057 Granulocyte Colony-Stimulating Factor-Producing Malignant Pleural Mesothelioma: Report of Two Cases

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Granulocyte-colony stimulating factor (G-CSF) producing malignant pleural mesothelioma: Report of a case

This report presents a case of malignant pleural mesothelioma (MPM) producing granulocyte colony-stimulating factor (G-CSF) that was treated by tumor resection. A 76-year-old male presented with a huge right-side chest wall tumor, along with a slight fever and chest wall pain. Laboratory findings showed an increased white blood cell count (64600 cells/μL) and C-reactive protein level (20.57 mg/...

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Production of granulocyte colony-stimulating factor by malignant mesothelioma.

We present the case of a male patient, aged 45 yrs, with malignant mesothelioma producing granulocyte colony-stimulating factor (G-CSF). The diagnosis was established by histopathological examination of the autopsied pleural tissues. Production of G-CSF was confirmed by immunoperoxidase staining, using a specific monoclonal antibody against recombinant G-CSF (rhG-CSF).

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Granulocyte Colony-Stimulating Factor-Producing Gallbladder Cancer.

We report a case of a granulocyte colony-stimulating factor (G-CSF)-producing gallbladder tumor associated with fever in a middle-aged female. Preoperative blood analysis showed leukocytosis with elevated levels of C-reactive protein and G-CSF. We resected the liver at S4a+S5, with regional lymph node dissection and partial resection of the duodenum. Histology revealed undifferentiated carcinom...

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Granulocyte-colony stimulating factor producing rectal cancer

BACKGROUND Granulocyte-colony stimulating factor (G-CSF)-producing cancer has been reported to occur in various organs, especially the lung. However, G-CSF-producing colorectal cancer (CRC) has never been reported in the English literature. CASE PRESENTATION A 57-year-old man was admitted for the surgical removal of a rectal cancer. Some hepatic tumors in the liver were revealed concurrently,...

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Granulocyte-colony-stimulating factor producing esophageal squamous cell carcinoma: a report of 3 cases

Although different types of granulocyte-colony-stimulating factor (G-CSF)-producing carcinomas have been reported, G-CSF-producing esophageal squamous cell carcinoma (SCC) is extremely rare. The prognosis of G-CSF-producing esophageal cancer has generally been reported to be very poor. Here, we report three cases of G-CSF-producing SCC who were successfully treated by use of multimodal therapy.

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2017

ISSN: 1556-0864

DOI: 10.1016/j.jtho.2016.11.1956